Cosmetic innovation — using Pichia pastoris to restore collagen

2 March, 2026

Pichia pastoris is a species of methylotrophic yeast. It was discovered in the 1960s and has been widely used in biochemical research and the biotechnology industry.

In nature, P. pastoris is found on trees, such as chestnut trees. It can be easily cultivated and used in laboratory conditions. It has a relatively short life cycle and a high regeneration rate.

As an experimental model organism, P. pastoris has mainly been used for transformation studies. Due to its ability to combine with foreign DNA, specifically human skin DNA, it became possible to produce recombinant collagen — Pure Collagen Feijia. Feijia contains 1.2% type III collagen obtained from Pichia pastoris after recombination with human DNA.

Thanks to modern biochemical technologies and single-cell microorganisms, we can help replenish collagen loss in the skin within the field of aesthetic cosmetology.

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